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Product introduction
C-021 dihydrochloride 是有效的 CC 趋化因子受体 4 (CCR4) 拮抗剂。C-021 dihydrochloride 有效抑制人和小鼠的功能趋化性,IC50 分别为 140 nM 和 39 nM。C-021 dihydrochloride 以 IC50 为 18 nM 来有效阻止人 CCL22 衍生的 [35S]GTPγS 与受体结合。 Product description: C-021 dihydrochloride is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 dihydrochloride effectively prevents human CCL22-derived [35S]GTPγS from binding to the receptor with an IC50 of 18 nM.
Chinese name
C 021 二盐酸盐
English name
C 021 dihydrochloride
Chinese alias
2-[1,4'-联哌啶] -1'-基-N-环庚基-6,7-二甲氧基-4-喹唑啉胺盐酸盐
English alias
2-[1,4'-Bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine dihydrochloride
CAS number
1784252-84-1
molecular formula
C27H41N5O2•2HCl
molecular weight
540.57 g/mol
Exact mass
≥99%(HPLC)
PSA
62.800 Ų
Logp
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Research chemical 100mg; ≥99%; HPLC

Research chemical 100mg; ≥99%; HPLC; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 100mg; ≥99%; HPLC.

item number:C288233-100mg
Product model:100mg
level: 100mg; ≥99%; HPLC
Lead Time:30days
sold 796 Items
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Specifications:

100mg

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