
- Health hazard: 急/慢性危害:该化合物可能引起眼睛刺激。加热至分解时会产生氮氧化物和氯化氢的有毒烟雾。(NTP, 1992)
- reactive group: 盐类,碱性
- First aid measures: 食入:不要催吐。如果受害者意识清醒且没有抽搐,给予1-2杯水稀释化学物质,并立即呼叫医院或中毒控制中心。如果医生建议,准备将受害者送往医院。如果受害者抽搐或昏迷,不要经口给予任何东西,确保受害者的气道通畅,让受害者侧卧,头部低于身体。不要催吐。立即将受害者送往医院。(NTP, 1992)
- exposure pathway: 口服剂量的不到20%从胃肠道吸收。
- Toxicity summary: 阿糖胞通过直接 DNA 损伤和掺入 DNA 发挥作用。阿糖胞对培养中各种增殖的哺乳动物细胞具有细胞毒性。它表现出细胞周期特异性,主要杀死正在进行 DNA 合成(S 期)的细胞,并在特定条件下阻止细胞从 G1 期进入 S 期。尽管作用机制尚未完全理解,但阿糖胞似乎是通过抑制 DNA 聚合酶发挥作用。据报道,阿糖胞有限但显著地掺入 DNA 和 RNA 中。
- Regulatory information: REACH注册物质:状态:活跃 更新:2017-12-12 https://echa.europa.eu/registration-dossier/-/registered-dossier/21560
- fire hazard: 该化学品的闪点数据不可用;但可能是可燃的。(NTP, 1992)
- fire fighting: 涉及此材料的火灾可用干粉、二氧化碳或哈龙灭火器控制。(NTP, 1992)
- Toxicity Data: 可能发生阿糖胞综合征 - 其特征为发热、肌痛、骨痛、偶有胸痛、斑丘疹、结膜炎和不适。 <<<130>>氯生定是异吲哚的成员。
- reactivity profile: 阿糖胞盐酸盐在酸性溶液中会发生分解。
- Air and water reaction: 水溶性。水解容易发生,特别是在酸性条件下。
- Hazard categories and classifications: 生殖毒性 2 (100%)
- Non-fire leakage response: 储存注意事项:您应将此材料存放在冰箱中。(NTP, 1992)
- Personal protective equipment (PPE): 推荐呼吸器:在称量和稀释纯测试化学品时,佩戴NIOSH批准的半面罩呼吸器,配备有机蒸气/酸性气体 cartridges(专门用于有机蒸气、HCl、酸性气体和SO2)和粉尘/雾过滤器。(NTP,1992)
- Carcinogen Classification: 对人类无致癌性迹象(未被IARC列出)。
- Effects During Pregnancy and Lactation: 截至修订日期,未找到相关已发表信息。
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Research chemical 1ml
Research chemical 1ml; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1ml.
1ml




