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Product introduction

Crolibulin (EPC2407) is a tubulin polymerization inhibitor, with potent apoptosis induction and cell growth inhibition. Crolibulin has anti-tumor activity. Crolibulin also has cardiovascular toxicity and neurotoxicity In Vitro Crolibulin shows significant cytotoxic activity against HT-29 cells, with an IC 50 of 0.52 μM. Crolibulin is active against various experimental tumors and exhibit potent inhibition of mitosis at the G2/M stage. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Tubulin polymerization

Specs ⸢ View details ⸥

Chinese name

Crolibulin, 微管蛋白抑制剂

English name

Crolibulin

Chinese alias

克罗利布林

English alias

(R)-2,7,8-triamino-4-(3-bromo-4,5-dimethoxyphenyl)-4H-chromene-3-carbonitrile | EPC2407 | EPC-2407 | Q252344 | D09882 | 1000852-17-4 | AT-20GF | JXONINOYTKKXQQ-CQSZACIVSA-N | BG0 | CROLIBULIN [WHO-DD] | UNII-9ENT43KY91 | Q27272449 | CROLIBULIN [INN] | EX-

CAS number

1000852-17-4

molecular formula

C18H17BrN4O3

molecular weight

417.26 g/mol

Exact mass

≥98%

PSA

130.000 Å²

Logp

2.6

Technical Documents

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