CBP/p300-IN-10 is a highly potent histone acetyltransferase EP300 and CREBBP with IC 50 values of 26 nM and 39 nM, respectively. CBP/p300-IN-10 can be used to research anticancer In Vitro CBP/p300-IN-10 (example 84) (0-1 μM; 3 h) inhibit H3K27Ac activity in LK2 cells with an IC 50 of 22 nM. CBP/p300-IN-10 (38 nM-10 mM; 3 days) has inhibitory activity against LK2 and TE-8. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Proliferation AssayCell Line: LK2 and TE-8 Concentration: 38 nM-10 mM Incubation Time: 3 days Result: Inhibited LK2 and TE-8 with GI 50 s of 97.163 nM and 152.484 nM, respectively. Form:Solid IC50& Target:EP300 26 nM (IC 50 ) CREBBP 39 nM (IC 50 )