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Product details

名称

CMF019

分子类型

未知

英文名称

CMF019

货号

C650180-5mg

包装规格

5mg

浓度

≥99%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

CMF019 is a potent and small molecule agonist at Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ with pKi values of 8.58, 8.49 and 8.71 for human, rat, and mouse, respectively. CMF019 mimics the beneficial cardiovascular actions of apelin in rodents Apelin receptor (APJ) is a G protein-coupled receptor (GPCR) activated by the endogenous peptide apelin . Form:Solid IC50& Target:pKi: 8.58 (human Apelin receptor) ,8.49 (rat Apelin receptor),8.71 (mouse Apelin receptor)

生化机理

CMF019 是一种具有 G 蛋白偏向的 Apelin 受体（APJ）强效小分子激动剂。CMF019 与 APJ 的结合 pKi 值分别为 8.58、8.49 和 8.71（人、大鼠和小鼠）。CMF019 可模拟芹菜素对心血管的有益作用

CAS号

1586787-08-7

分子式

C25H33N3O3S

分子量

455.61 g/mol

Smiles

CC(C)C[C@H](NC(C1=CC=C2C(N=C(CC3=CC=CS3)N2C(CC)CC)=C1)=O)CC(O)=O

溶解性

DMSO : 50 mg/mL (109.74 mM; Need ultrasonic)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

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「No related articles yet」

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