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Product introduction

(5Z,2E)-CU-3 is a potent and selective inhibitor against the α-isozyme of DGK with an IC 50 value of 0.6 μM, competitively inhibits the affinity of DGKα for ATP with a K m value of 0.48 mM. (5Z,2E)-CU-3 targets the catalytic region, but not the regulatory region of DGKα. (5Z,2E)-CU-3 has antitumoral and proimmunogenic effects, enhances the apoptosis of cancer cells and the activation of T cells Form:Solid IC50& Target:IC50: 0.6 μM (DGKα)

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Chinese name

(5Z,2E)-CU-3

English name

(5Z,2E)-CU-3

Chinese alias

English alias

CAS number

1815598-71-0

molecular formula

C16H12N2O4S3

molecular weight

392.47 g/mol

Exact mass

≥95%

PSA

145.000 Å²

Logp

3.600

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