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Product details

名称

CCT367766 formic

别名

CCT367766 甲酸

英文名称

CCT367766 formic

货号

C658718-5mg

包装规格

5mg

浓度

≥98%

储存温度

-20°C储存,干燥

运输条件

超低温冰袋运输

产品介绍

CCT367766 formic is a potent and the third generation heterobifunctional and Cereblon -based pirin targeting protein degradation probe (PDP, or PROTAC), depletes pirin protein expression at low concentration. CCT367766 formic exhibits a moderate affinity Appearance:Solid IC50& Target:CRBN-DDB1 490 nM (IC 50 ) In Vitro:CCT367766 formic (50-1500 nM; 24 hours) demonstates the depletion of pirin protein as a the time-dependent hook-effect in SK-OV-3 human ovarian cancer cells. CCT367766 formic (0.5-50 nM; 2 hours) demonstrates the concentration-dependent depletion of Biological Activity:CCT367766 formic is a potent and the third generation heterobifunctional and Cereblon -based pirin targeting protein degradation probe (PDP, or PROTAC), depletes pirin protein expression at low concentration. CCT367766 formic exhibits a moderate affinity

分子式

C50H50ClN7O13

分子量

992.42 g/mol

Smiles

O=C(C1=CC=C2N=C(CN3CCN(CCOCCOCCOC4=CC=CC(C(N5C(CC6)C(NC6=O)=O)=O)=C4C5=O)CC3)C=CC2=C1)NC7=CC(NC(C8=CC=C(OCCO9)C9=C8)=O)=CC=C7Cl.OC=O

溶解性

DMSO : ≥ 250 mg/mL (251.91 mM)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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