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Product details

名称

β-CGRP, human TFA

分子类型

肽

英文别名

Human β-CGRP TFA | CGRP-II (Human) TFA

英文名称

β-CGRP, human TFA

货号

C659059-5mg

包装规格

5mg

浓度

≥98%

储存温度

-20°C储存,干燥

运输条件

超低温冰袋运输

敏感性

易吸潮

产品介绍

β-CGRP, humanTFA是一种降钙素肽，通过降钙素受体样受体CRLR与RAMP的复合物起作用，在细胞体系中，对CRLR/RAMP1和CRLR/RAMP2的IC50值分别为1nM和300nM。序列： Ala-Cys-Asn-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Met-Val-Lys-Ser-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2(Disulfide bridge: Cys2-Cys7) 简短序列： ACNTATCVTHRLAGLLSRSGGMVKSNFVPTNVGSKAF-NH2(Disulfide bridge: Cys2-Cys7) β-CGRP, human TFA (Human β-CGRP TFA) is one of calcitonin peptides , acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC 50 s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells. Appearance:Solid IC50& Target:IC50: 1 nM (CRLR/RAMP1, cell assay), 300 nM (CRLR/RAMP2, cell assay) In Vitro:β-CGRP, human is one of calcitonin peptides, acts via complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC 50 s of 1 nM in both SK-N-MC and Swiss 3T3 cells express CRLR and RAMP1, and 130 nM and 300 n Biological Activity:β-CGRP, human TFA (Human β-CGRP TFA) is one of calcitonin peptides , acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC 50 s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells.

CAS号

101462-82-2(free base)

分子式

C162H267N51O48S3.xC2HF3O2

分子量

3793.41 (free base) g/mol

溶解性

H2O : 25 mg/mL (6.40 mM; Need ultrasonic)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

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「No related articles yet」

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