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名称

Compstatin TFA

别名

康普他汀

英文名称

Compstatin TFA

货号

C659076-5mg

包装规格

5mg

浓度

≥99%

储存温度

避光,干燥,-80℃储存

运输条件

超低温冰袋运输

产品介绍

Compstatin TFA, a 13-residue cyclic peptide, is a potent inhibitor of the complement system C3 with species specificity. Compstatin TFA binds to baboon C3 and is resistant to proteolytic cleavage in baboon blood (similar to humans). Compstatin TFA inhibit Appearance:Solid In Vitro:Compstatin exhibits an in vitro half-life in human blood of about 2 hr. In solution, compstatin forms a β-turn at residues Gln-5–Gly-8 with the disulfide bridge Cys-2–Cys12, residues Ile-1–Val-4, and Thr-13, forming a hydrophobic cluster. MCE ha In Vivo:Compstatin (21mg/kg) produces complete inhibition when given as a combination of bolus injection and infusion. Compstatin completely inhibits in vivo heparin/protamine-induced complement activation without adverse effects on heart rate or systemic arteri Biological Activity:Compstatin TFA, a 13-residue cyclic peptide, is a potent inhibitor of the complement system C3 with species specificity. Compstatin TFA binds to baboon C3 and is resistant to proteolytic cleavage in baboon blood (similar to humans). Compstatin TFA inhibit

分子式

C68H100F3N23O19S2

分子量

1664.79 g/mol

溶解性

DMSO : 110 mg/mL (66.07 mM; Need ultrasonic) H2O : 50 mg/mL (30.03 mM; Need ultrasonic)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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