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Product introduction
CU-T12-9 是一种特异性 TLR1/2 激动剂,EC50 为 52.9 nM。CU-T12-9 既激活先天免疫系统,又激活适应性免疫系统。CU-T12-9 选择性激活 TLR1/2 异二聚体而对 TLR2/6 没有作用。CU-T12-9 通过促进 TLR1 和 TLR2 二聚而激活 NF-κB 信号,致使下游 TNF-α,IL-10,和 iNOS 增加,从而提高身体的免疫反应。 CU-T12-9 is a specific TLR1/2 agonist with EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay. CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 selectively activates the TLR1/2 heterodimer, not TLR2/6. CU-T12-9 signals through NF-κB and invokes an elevation of the downstream effectors TNF-α, IL-10, and iNOS.
Chinese name
CU-T12-9,TLR1 / 2激动剂
English name
CU-T12-9
Chinese alias
N-甲基-4-硝基-2-(4-(4-三氟甲基)苯基)-1H-咪唑-1-基)苯胺
English alias
N-Methyl-4-nitro-2-(4-(4-trifluoromethyl)phenyl)-1H-imidazol-1-yl)aniline
CAS number
1821387-73-8
molecular formula
C17H13F3N4O2
molecular weight
362.31 g/mol
Exact mass
≥98%
PSA
75.700 Ų
Logp
4
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CU-T12-9 10mM in DMSO 1ml

Macklin CU-T12-9 10mM in DMSO 1ml, CAS 1821387-73-8, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:C687754-1ml
Product model:1ml
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Lead Time:30days
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