胶原酶 来源于溶组织梭菌

梭菌肽酶 A

C754929-25mg

25mg

天然

suitable for release of physiologically active rat epididymal adipocytes, 0.5-5.0 FALGPA U/mg solid, ≥125 CDU/mg solid

胶原酶可用于：研究晚期糖基化终产物（AGE）的动脉组织的制备与其他蛋白酶一起用于人类肿瘤、小鼠肾脏、人脑、肺上皮和许多其他组织的解聚。肝脏和肾脏的灌注研究、胰腺的消化和非实质肝细胞的分离从大鼠肝脏制备活的肝细胞以及从大鼠脂肪组织中分离脂肪细胞应用： 溶组织梭菌是一种可产生胶原酶的致病性梭菌。这是一种含有胶原酶、非特异性蛋白酶和梭菌蛋白酶的酶混合物。 Clostridium histolyticum is a pathogenic clostridium that produces collagenase. This is a mixture of enzymes containing collagenase, non-specific proteases and clostripain. Application: Collagenase may be used: for the preparation of arterial tissue for the study of advanced glycosylation end products (AGE) for use along with other proteases for the disaggregation of human tumor, mouse kidney, human brain, lung epithelium and many other tissues. in liver and kidney perfusion studies, digestion of pancreas, and isolation of nonparenchymal hepatocytes for the preparation of viable hepatocytes from rat liver and for the isolation of fat cells from rat adipose tissue

每摩尔的胶原酶可被四克的钙原子所激活。它可被乙二醇-双（β-氨基乙基醚）-N,N,N′,N′-四乙酸、β-巯基乙醇、谷胱甘肽，巯基乙酸和8-羟基喹啉所抑制。胶原酶和中性蛋白酶在从组织中进行细胞的有效释放中都可起到重要作用。 胶原酶可识别-R-Pro-8-X-Gly-Pro-R-序列，其中X大多数情况下是一种中性氨基酸。每摩尔胶原蛋白酶被4g原子钙活化。 它被乙二醇-双（β-氨基乙基醚）-N，NN′,N′-四乙酸，β-巯基乙醇、谷胱甘肽、巯基乙酸和8-羟基喹啉抑制。

0.5-5.0 FALGPA U/mg solid, ≥125 CDU/mg solid

天然

溶组织梭菌(Clostridium histolyticum)