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名称

胰凝乳蛋白酶来源于人类胰腺

货号

C755275-100μg

包装规格

100μg

浓度

≥95%(SDS-PAGE)

产品介绍

来自人胰腺的胰凝乳蛋白酶是一种丝氨酸肽酶，其具有241 个氨基酸残基，包含通过二硫键连接的三条多肽链（A 链-13 残基、B 链-131 残基和 C 链-97 残基）。它被胰腺分泌为无活性的胰凝乳蛋白酶原C。该酶的分子量为25kDa。pI 是 8.75。 Chymotrypsin from human pancreas is a serine peptidase and has 241 amino acid residues contained in three polypeptide chains (A chain-13 residues, B chain-131 residues, and C chain-97 residues) linked by disulfide bridges. It is secreted by the pancreas as inactive chymotrypsinogen C. Molecular weight of this enzyme is found to be 25kDa. The pI is 8.75.

生化机理

来自人胰腺的胰凝乳蛋白酶可选择性地水解酪氨酸、苯丙氨酸、色氨酸和亮氨酸的C端侧的肽键。该基因的功能丧失突变与慢性胰腺炎的风险增加有关。它对亮氨酰肽键具有高活性。该酶可充当羧肽酶A1和A2的共激活因子。

Safety

「No Dangerous Attributes」

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