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Product details
名称
羧肽酶 G 来源于假单胞菌 属
货号
C755300-20units
包装规格
20units
浓度
lyophilized powder,≥3 units/mg protein
产品介绍
来自假单胞菌属或 γ-谷氨酰基水解酶的羧肽酶 G 已用于研究中评估假单孢氧还蛋白 COOH-末端在 P-450cam(细胞色素 m)羟基化中的作用。来源于假单胞菌属的羧肽酶 G 也被用于研究肺腺癌细胞中一氧化氮通过 NO‑cGMP 信号通路对培美曲塞细胞毒性的产生影响。 Carboxypeptidase G from Pseudomonas sp. , or γ-Glutamyl hydrolase, has been used in a study to assess the role of the putidaredoxin COOH-terminus in P-450cam (cytochrome m) hydroxylations. Carboxypeptidase G from Pseudomonas sp. has also been used in a study to investigate the effects of nitric oxide on pemetrexed cytotoxicity via NO‑cGMP signaling in lung adenocarcinoma cells.
生化机理
羧肽酶 G 是溶酶体,巯基依赖性蛋白酶,其逐渐切割 γ-谷氨酰蝶酰多聚-γ-谷氨酸,产生蝶酰-α-谷氨酸(叶酸)和游离谷氨酸。它被认为对 γ-谷氨酰基键具有高度特异性,但对于离去基团的 C-末端氨基酸则不具有高度特异性。 该同型二聚体的分子量约为 90kDa。酶被 Zn 2+ 离子激活。
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「No Dangerous Attributes」
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Research chemical

Research chemical; supplied for laboratory research, analysis, inspection, and scientific procurement use.

item number:C755300-20units
Product model:20units
level: lyophilized powder, ≥3 units/mg protein
Lead Time:30days
sold 871 Items
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20units

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