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Product introduction
氯氮平N-氧化物(CNO),氯氮平药物的非激活形式,可活化G蛋白偶联受体(GPCR)。[1]CNO看作为工程化人毒蕈碱受体的合成配体。它在代谢转化时可引起类似氯氮平的作用。[2]氯氮平转化为CNO将有利于其通过血脑屏障 应用 氯氮平N-氧化物已用于: 在初级运动皮层中激活人M4毒蕈碱(hM4Di) 在Th-cre转基因小鼠中诱导体内化学遗传性操控并损伤运动活性 小鼠中的行为测试和刺激(HEK293)细胞
Chinese name
氯氮平N-氧化物
English name
ClozapineN-Oxide
Chinese alias
8-氯-11-(4-甲基-1-哌嗪基)-5H-二苯并[b,e](1,4)二氮杂N-氧化物 | 8-氯-11-(4-甲基-4-氧化-1-哌嗪基)-5H-二苯并[b,e][1,4]二氮杂卓 | 4-(8-氯-5H-二苯并[b,e][1,4]二氮杂卓-11-基)-1-甲基哌嗪1-氧化物
English alias
N-Oxyclozapine | s4107 | UNII-MZA8BK588J | 1-[3-(dimethylamino) propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran carbonitrile | BC162765 | BDBM50279241 | 8-chloro-11-(4-methyl-4-oxo-4lambda~5~-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine | 8-Chloro
CAS number
34233-69-7
molecular formula
C18H19ClN4O
molecular weight
342.82 g/mol
Exact mass
≥97%
PSA
45.700 Ų
Logp
2.500
Technical Documents
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Clozapine (N-oxide) 10mM in DMSO 1ml

Clozapine (N-oxide) 10mM in DMSO 1ml Macklin 34233-69-7, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number:C766704-1ml
Product model:1ml
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Lead Time:30days
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