
- DOT label: 毒物
- Health hazard: 口服高度毒性。(EPA, 1998)
- Storage conditions: 当缓冲至pH 3.5时,水溶液在高压灭菌时最稳定。未缓冲溶液在高压灭菌时可能发生高达5%的分解,并且分解会增加溶液的pH值;这种高压灭菌后的溶液不应储存超过一年。
- reactive group: 季铵盐和鏻盐
- First aid measures: 5. 转移到医疗机构。(EPA, 1998)
- Regulatory information: 新西兰EPA化学品清单状态: 氯化氨甲酰胆碱: 没有单独批准但可在适当的团体标准下使用
- fire hazard: 加热分解时,会释放出氯化物和氮氧化物的剧毒烟雾。水溶液即使加热也是稳定的。(EPA, 1998)
- fire fighting: FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. (ERG, 2024)
- interaction: 同时使用.../眼科颠茄生物碱或环戊醇/可能干扰卡巴胆碱的抗青光眼作用;同时使用卡巴胆碱也会抵消这些药物的散瞳作用...。
- reactivity profile: 卡巴胆碱盐酸盐是一种氨基甲酸酯。氨基甲酸酯在化学上类似于酰胺,但反应性更强。与酰胺类似,它们可形成聚合物,如聚氨酯树脂。氨基甲酸酯与强酸和强碱不相容,尤其与强还原剂如氢化物不相容。活性金属或氮化物与氨基甲酸酯结合会产生易燃的氢气。强氧化性酸、过氧化物和氢过氧化物与氨基甲酸酯不相容。
- Isolation and evacuation: 火灾:如果涉及罐、铁路罐车或公路罐车,应在所有方向上隔离800米(1/2英里);同时,考虑在所有方向上初始疏散800米(1/2英里)。(ERG, 2024)
- FDA Requirements: 《具有治疗等效性评估的批准药物产品清单》确定了当前上市的药物产品,包括卡巴胆醇,这些产品是根据联邦食品、药品和化妆品法案第505和507条,FDA基于安全性和有效性批准的。/附录A,产品名称索引/
- Human toxicity extract: 将0.01%的溶液引入人眼前房...的测试显示没有显著的刺激或伤害作用,但有快速的缩瞳效果。
- Other safety information: 化学品评估:IMAP评估 - 乙铵,2-[(氨基甲酰基)氧基]-N,N,N-三甲基-, 氯化物:人类健康I级评估
- Air and water reaction: 吸湿性。
- non-human toxicity value: LD50 小鼠静脉注射 0.3 mg/kg
- Hazard categories and classifications: 急性毒性 2类(100%)
- Non-human toxic extract: 将0.01%溶液引入兔、猫眼睛前房的测试显示没有明显的刺激或伤害作用,但有快速的缩瞳效果。
- Non-fire leakage response: 避免皮肤接触。(EPA, 1998)
- Personal protective equipment (PPE): 紧急情况下,佩戴正压、需求式、全面罩自给式呼吸器(SCBA)或需求式供气呼吸器,并配备逃生SCBA和全包覆式耐化学腐蚀服。(EPA, 1998)
- Antidote and first aid: 硫酸阿托品注射液用作卡巴胆碱全身作用的解毒剂。
- Protective Action Standards (PAC): PAC-3: 90 [mg/m3]
- Effects During Pregnancy and Lactation: 截至修订日期,未找到关于哺乳期妇女的相关已发表信息。在动物实验中,胆碱能药物会增加催产素的释放,并对血清催乳素水平产生不同影响。对于已建立哺乳期的母亲,其催乳素水平可能不会影响其母乳喂养能力。
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Research chemical 1g; ≥99%
Research chemical 1g; ≥99%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1g; ≥99%.
1g




