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Product introduction
Cabozantinib (XL184, BMS-907351)是一种有效的VEGFR2抑制剂,靶向作用于VEGFR2和c-Met时,IC50为0.035 nM ,也有效抑制c-Met、 Ret、 Kit、Flt-1/3/4、Tie2和AXL,IC50分别为1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM。A potent VEGFR2 and Met inhibitor Cabozantinib (XL184, BMS-907351) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. A potent VEGFR2 and Met inhibitor
Chinese name
卡博替尼 (XL184, BMS-907351), 激酶插入域受体抑制剂
English name
Cabozantinib (XL184, BMS-907351)
Chinese alias
-
English alias
BDBM50021574 | N-[4-[(6,7-Dimethoxyquinolin-4-yl)oxy]phenyl]-N inverted exclamation mark -(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | XL-184 free base (Cabozantinib) | BMS 907351 | FT-0664184 | AKOS025142112 | N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)ph
CAS number
849217-68-1
molecular formula
C28H24FN3O5
molecular weight
501.52 g/mol
Exact mass
-
PSA
98.800 Ų
Logp
5.400
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Qia Bo Ti Ni >=99. 5% 1g

Qia Bo Ti Ni >=99. 5% 1g Macklin 849217-68-1, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

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