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Product introduction

Dynasore是一种可渗透细胞的，可逆的，非竞争性的dynamin（发动蛋白）抑制剂，抑制dynamin 1/2的GTPase活性，IC50为15 μM，也抑制线粒体dynamin Drp1，对其他小GTP酶没有作用效果。An inhibitor of Dynamin I and Dynamin II Dynasore is a cell-permeable, reversible non-competitive dynamin inhibitor of GTPase activity of dynamin 1/2, with IC50 of 15 μM, also inhibits the mitochondrial dynamin Drp1, with no effect against other small GTPase An inhibitor of Dynamin I and Dynamin II

Specs ⸢ View details ⸥

Chinese name

3-羟基-萘-2-羧酸（3,4-二羟基-亚苄基）-酰肼

English name

Dynasore

Chinese alias

3-羟基萘-2-羧酸(3,4-二羟基苯亚甲基)酰肼 | N'-(3,4-二羟基苯亚甲基)-3-羟基-2-萘甲酰肼 | 动力抑制剂I

English alias

CAS number

304448-55-3

molecular formula

C18H14N2O4

molecular weight

322.31 g/mol

Exact mass

≥98%

PSA

102.000 Å²

Logp

3.6

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