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Product introduction

Deruxtecan-d4 是氘代标记的 Deruxtecan。Deruxtecan 是毒性药物和 linker 的偶联物。毒性药物是 DX-8951 的衍生物 (Dxd)，linker 是马来酰亚胺-GGFG 肽。Deruxtecan 可用于合成 DS-8201 和 U3-1402。体外研究氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱。 Deruxtecan-d4 is deuterium labeled Deruxtecan. Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402. In vitro research MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Specs ⸢ View details ⸥

Chinese name

Deruxtecan-d

English name

Deruxtecan-d

Chinese alias

English alias

CAS number

2760715-91-9

molecular formula

C52H52D4FN9O13

molecular weight

1038.08 g/mol

Exact mass

PSA

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