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Product introduction

DCB是代谢型谷氨酸受体mGluR-5的变构配体，并显示中性调节作用。DCB不会影响激动剂刺激的mGluR-5反应，但会阻止其他变构调节剂（例如DFB和DMeOB）对受体的调节。 DCB is an allosteric ligand for the metabotropic glutamate receptor mGluR-5 and displays neutral modulation. DCB does not affect agonist-stimulated mGluR-5 responses, but blocks regulation of the receptor by other allosteric modulators such as DFB and DMeOB .

Specs ⸢ View details ⸥

Chinese name

DCB

English name

DCB

Chinese alias

3,3′-二氯苯甲嗪 | NSC 67224

English alias

3,3'-dichlorobenzaldazine

CAS number

6971-97-7

molecular formula

C14H10Cl2N2

molecular weight

277.15 g/mol

Exact mass

≥98%

PSA

24.700 Å²

Logp

4.600

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