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Product introduction
双环维林是1-环己基环己烷甲酸与2-(二乙氨基)乙醇缩合形成的酯。作为一种抗胆碱药,它以盐酸盐形式用于治疗或预防胃肠道肌肉痉挛,特别是与肠易激综合征相关的痉挛。它具有毒蕈碱拮抗剂、抗胆碱能和解痉药物的作用。它是一种叔胺和羧酸酯。它在功能上与2-二乙氨基乙醇和1,1'-联(环己基)-1-羧酸相关。
Chinese name
dicyclomine, M 1 受体拮抗剂
English name
2-(diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate
Chinese alias
-
English alias
BPBio1_000193 | DICYCLOVERINE [WHO-DD] | Tox21_113571 | CAS-67-92-5 | NCGC00015368-06 | AB00053456_15 | CHEBI:4514 | D07820 | DICYCLOMINE [VANDF] | KBio2_001414 | Prestwick3_000048 | 2-(DIETHYLAMINO)ETHYL (BICYCLOHEXYL)-1-CARBOXYLATE | Bentyl | Dicyclover
CAS number
77-19-0
molecular formula
C19H35NO2
molecular weight
309.5
Exact mass
-
PSA
29.5
Logp
5.5
Safety
  • Regulatory information: REACH 注册物质:状态:活跃 更新:15-03-2016 https://echa.europa.eu/registration-dossier/-/registered-dossier/17177
  • interaction: ...抗胆碱能药物,如...双环胺...预计会与地高辛相互作用...
  • Hepatotoxicity: 药物类别:抗胆碱能药物
  • Human toxicity extract: 研究了怀孕期间服用含有10 mg盐酸双环胺的苯海拉明的女性后代出生缺陷的发生率。追踪了2,298例分娩,并将缺陷发生率与相关人群进行比较。未发现致畸性证据。
  • Other safety information: 化学品评估:IMAP评估 - [1,1'-联环己基]-1-羧酸,2-(二乙氨基)乙酯:人类健康I级评估
  • Hazard categories and classifications: 急性毒性4级(100%)
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
  • Effects During Pregnancy and Lactation: 截至修订日期,未找到关于哺乳期母亲的已发表相关信息。抗胆碱能药物可抑制动物泌乳,显然是通过抑制生长激素和催产素分泌。抗胆碱能药物也可降低非哺乳期妇女的血清催乳素。已建立泌乳的母亲体内的催乳素水平可能不会影响她母乳喂养的能力。
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dicyclomine, M 1 receptorantagonist; M 2 receptorantagonist; M 3 receptorantagonist; M 4 receptorantagonist 5mg

dicyclomine, M 1 receptorantagonist; M 2 receptorantagonist; M 3 receptorantagonist; M 4 receptorantagonist 5mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 5mg.

item number:D609875-5mg
Product model:5mg
level: 5mg
Lead Time:30days
sold 809 Items
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5mg

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