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Product introduction

DYRKs-IN-1 hydrochloride is a potent DYRKs (Dual-specificity tyrosine-phosphorylation-regulated kinases) inhibitor with IC 50 s of 5 nM and 8 nM for DYRK1A and DYRK1B, respectively. DYRKs-IN-1 hydrochloride has antitumor activity In Vitro DYRKs-IN-1 hydrochloride (compound 30) increases the cellular potency against the human colon tumor cell line SW 620 with an EC 50 of 27 nM. DYRKs-IN-1 hydrochloride (Example 183) is a potent DYRKs inhibitor. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:DYRK1A 5 nM (IC 50 ) DYRK1B 8 nM (IC 50 )

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Chinese name

DYRKs-IN-1 hydrochloride

English name

DYRKs-IN-1 hydrochloride

Chinese alias

DYRKs-IN-1 盐酸盐

English alias

CAS number

1386980-55-7

molecular formula

C30H31Cl2N7O4

molecular weight

624.52 g/mol

Exact mass

≥99%

PSA

Logp

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