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Product details

名称

DSHS00884

分子类型

小分子

英文别名

英文名称

DSHS00884

货号

D648822-5mg

包装规格

5mg

浓度

≥99%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

DSHS00884 is a potent human papillomavirus E6 inhibitor with an IC 50 of 10 μM In Vitro DSHS00884 stabilizes p53 levels in HPV-positive cells by blocking E6-mediated p53 degradation with an IC 50 of 2.5-25 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 10 μM (human papillomavirus E6)

生化机理

DSHS00884 是一种强效的人类乳头瘤病毒 E6 抑制剂，IC50 为 10 μM。

CAS号

675104-49-1

分子式

C12H12N4O2S2

分子量

308.38 g/mol

PubChem编号

2807230

Isomeric SMILES

C=CCN1C(=NNC1=S)CSC2=CC=CC=C2[N+](=O)[O-]

IIUPAC Name

3-[(2-nitrophenyl)sulfanylmethyl]-4-prop-2-enyl-1H-1,2,4-triazole-5-thione

INCHI

1S/C12H12N4O2S2/c1-2-7-15-11(13-14-12(15)19)8-20-10-6-4-3-5-9(10)16(17)18/h2-6H,1,7-8H2,(H,14,19)

InChi Key

VWFIHGWHMXSTAO-UHFFFAOYSA-N

Smiles

C=CCN1C(=NNC1=S)CSC2=CC=CC=C2[N+](=O)[O-]

PubChem CID

2807230

关联CAS

675104-49-1

MeSH Entry Terms

3-((2-nitrophenyl)sulfanylmethyl)-4-prop-2-enyl-1H-1,2,4-triazole-5-thione;SSYA10-001

溶解性

DMSO : 250 mg/mL (810.69 mM; Need ultrasonic)

氢键供体数Hydrogen Bond Donor Count

氢键受体数Hydrogen Bond Acceptor Count

可旋转键计数Rotatable Bond Count

精确质量Exact Mass

308.04 Da

单同位素质量Monoisotopic Mass

308.04 Da

拓扑极表面积Topological Polar Surface Area

131.000 Å²

重原子数Heavy Atom Count

形式电荷Formal Charge

复杂度Complexity

436

同位素原子数Isotope Atom Count

共价键合单元计数Covalently-Bonded Unit Count

XLogP3

2.7

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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