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Product introduction

DOCK2-IN-1 (compound 3), a CPYPP analogue, is an inhibitor of DOCK2 as well ( IC 50 =19.1 μM). DOCK2-IN-1 binds to DOCK2 DHR-2 domain in a reversible manner to inhibits its catalytic activity. DOCK2-IN-1 blocks the activation of both chemokine receptor- and antigen receptor-mediated Rac in lymphocytes. DOCK2-IN-1 significantly suppresses chemotactic response and T cell activation Form:Solid IC50& Target:DOCK2

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Chinese name

DOCK2-IN-1

English name

DOCK2-IN-1

Chinese alias

English alias

CAS number

4590-86-7

molecular formula

C16H11ClN2O2

molecular weight

298.72 g/mol

Exact mass

≥96%

PSA

Logp

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