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Product details

名称

Didesmethyl cariprazine

别名

二去甲基卡利拉嗪

英文别名

英文名称

Didesmethyl cariprazine

货号

D651098-5mg

包装规格

5mg

浓度

≥99%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

Didesmethyl cariprazine is a metabolite of Cariprazine and acts as the predominant circulating active moiety. Didesmethyl cariprazine has a long half-life of 1-3 weeks. Cariprazine is a antipsychotic agent candidate that exhibits high affinity for the D 3 and D 2 receptors, and moderate affinity for the 5-HT 1A receptor Form:Solid IC50& Target:5-HT 1A Receptor D 3 Receptor D 2 Receptor

生化机理

双甲基卡哌嗪是卡哌嗪的代谢物，是主要的循环活性分子。双甲基卡哌嗪的半衰期较长，为 1-3 周。卡利普嗪是一种抗精神病候选药物，对 D 3

CAS号

839712-25-3

分子式

C19H28Cl2N4O

分子量

399.36 g/mol

PubChem编号

11200383

Isomeric SMILES

C1CC(CCC1CCN2CCN(CC2)C3=C(C(=CC=C3)Cl)Cl)NC(=O)N

IIUPAC Name

[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]urea

INCHI

1S/C19H28Cl2N4O/c20-16-2-1-3-17(18(16)21)25-12-10-24(11-13-25)9-8-14-4-6-15(7-5-14)23-19(22)26/h1-3,14-15H,4-13H2,(H3,22,23,26)

InChi Key

UMTWXZNVNBBFLC-UHFFFAOYSA-N

Smiles

C1CC(CCC1CCN2CCN(CC2)C3=C(C(=CC=C3)Cl)Cl)NC(=O)N

PubChem CID

11200383

关联CAS

839712-25-3

溶解性

DMSO : 11.36 mg/mL (28.45 mM; ultrasonic and warming and heat to 80°C)

氢键供体数Hydrogen Bond Donor Count

氢键受体数Hydrogen Bond Acceptor Count

可旋转键计数Rotatable Bond Count

精确质量Exact Mass

398.164 Da

单同位素质量Monoisotopic Mass

398.164 Da

拓扑极表面积Topological Polar Surface Area

61.600 Å²

重原子数Heavy Atom Count

形式电荷Formal Charge

复杂度Complexity

451

同位素原子数Isotope Atom Count

共价键合单元计数Covalently-Bonded Unit Count

XLogP3

3.7

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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