Share to

Details

Safety

Technical Documents

Articles

reviews

Consult

returns

Product details

名称

10β,17β-dihydroxyestra-1,4-dien-3-one

别名

10β,17β-二羟基雌甾-1,4-二烯-3-酮

英文别名

英文名称

10β,17β-dihydroxyestra-1,4-dien-3-one

货号

D651492-5mg

包装规格

5mg

浓度

≥98%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

10β,17β-dihydroxyestra-1,4-dien-3-one (DHED) is a brain-targeting bioprecursor proagent of the main human estrogen , 17β-estradiol, alleviates hot flushes in rat models of thermoregulatory dysfunction of the brain. In Vivo 10β,17β-dihydroxyestra-1,4-dien-3-one (DHED), is an inactive bioprecursor prodrug of 17β-estradiol converting to 17β-estradiol only in the brain. DHED as an E2-bioprecursor may be a viable approach for delivering E2 selectively into the brain for the potential treatment of hot flushes . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

生化机理

10β,17β-二羟基雌甾-1,4-二烯-3-酮（DHED）是人类主要雌激素 17β-estradiol 的一种脑靶向生物前体，它能缓解大鼠脑体温调节功能障碍模型中的潮热症状。

CAS号

549-02-0

分子式

C18H24O3

分子量

288.38 g/mol

PubChem编号

11851170

Isomeric SMILES

C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=CC(=O)C=C[C@]34O

IIUPAC Name

(8S,9S,10S,13S,14S,17S)-10,17-dihydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one

INCHI

1S/C18H24O3/c1-17-8-7-15-13(14(17)4-5-16(17)20)3-2-11-10-12(19)6-9-18(11,15)21/h6,9-10,13-16,20-21H,2-5,7-8H2,1H3/t13-,14-,15-,16-,17-,18+/m0/s1

InChi Key

UIKDFTLKOKNUJP-UGDFAFBOSA-N

Smiles

CC12CCC3C(C1CCC2O)CCC4=CC(=O)C=CC34O

PubChem CID

11851170

溶解性

DMSO : 100 mg/mL (346.76 mM; Need ultrasonic)

氢键供体数Hydrogen Bond Donor Count

氢键受体数Hydrogen Bond Acceptor Count

可旋转键计数Rotatable Bond Count

精确质量Exact Mass

288.173 Da

单同位素质量Monoisotopic Mass

288.173 Da

拓扑极表面积Topological Polar Surface Area

57.500 Å²

重原子数Heavy Atom Count

形式电荷Formal Charge

复杂度Complexity

549.000

同位素原子数Isotope Atom Count

共价键合单元计数Covalently-Bonded Unit Count

XLogP3

1.700

RIDADR

NONHforallmodesoftransport

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！

10β, 17β-dihydroxyestra-1, 4-dien-3-one 5mg

Name: 10β, 17β-dihydroxyestra-1, 4-dien-3-one 5mg
Brand: 阿拉丁
SKU: D651492-5mg

10β, 17β-dihydroxyestra-1, 4-dien-3-one 5mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 5mg; ≥98%.

item number：D651492-5mg

Product model：5mg

level： 5mg; ≥98%

Lead Time：30days

sold 15 Items

Ask Solution engineer

Specifications：

5mg

Qty

10β, 17β-dihydroxyestra-1, 4-dien-3-one 5mg

Recommended for you