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Product introduction

DUB-IN-2 is a potent deubiquitinase inhibitor with an IC 50 of 0.28 μM for USP8 In Vitro DUBs-IN-2 (compound 22 e) is a potent USP8 inhibitor with an IC 50 of 0.28 μM, and has no effect on USP7, with an IC 50 of >100 μM. DUBs-IN-2 inhibits the viability of HCT116 colon cell line and PC-3 prostate cancer cell line with IC 50 values of 0.5-1.5 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 0.28 μM (USP8)

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Chinese name

DUB-IN-2

English name

DUB-IN-2

Chinese alias

配音-2

English alias

CAS number

924296-19-5

molecular formula

C15H9N5O

molecular weight

275.26 g/mol

Exact mass

PSA

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