Share to

Details

Safety

Technical Documents

Articles

reviews

Consult

returns

Product details

名称

DC_517

英文名称

DC_517

货号

D654698-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

DC_517 is a DNA methyltransferase 1 ( DNMT1 ) inhibitor, with an IC 50 and a K d of 1.7 μM and 0.91 μM, respectively. In Vitro DC_517 is a DNA methyltransferase 1 (DNMT1) inhibitor, with an IC 50 and a K d of 1.7 μM and 0.91 μM, respectively. DC_517 (1.25, 2.5, 5, and 10 μM) potently inhibits the proliferation of HCT116 (human colon cancer) and Capan-1 (human pancreatic adenocarcinoma cells) after treatment for 24, 48, and 72 h. DC_517 (0, 0.75, 1.5, and 3 μM) also dose-dependently induces apoptotic cell death in HCT116 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:DNMT1 0.91 μM (Kd) DNMT1 1.7 μM (IC 50 )

生化机理

DC_517 是一种 DNA 甲基转移酶 1（DNMT1）抑制剂，其 IC 50 和 K d 分别为 1.7 μM 和 0.91 μM。

CAS号

500017-70-9(DMSO)

分子式

C33H35N3O2

分子量

505.65 g/mol

Smiles

OC(CNC(C)C)COC(CN1C(C=CC=C2)=C2C3=C1C=CC=C3)CN(C4=CC=CC=C45)C6=C5C=CC=C6

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！