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名称

4,5-Dimethoxycanthin-6-one

别名

4,5-二甲氧基肉桂酸-6-酮

英文名称

4,5-Dimethoxycanthin-6-one

货号

D655258-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

避光,-80℃储存

运输条件

超低温冰袋运输

产品介绍

4,5-Dimethoxycanthin-6-one is a potent and uncompetitive inhibitor of CYP1A2 -mediated phenacetin O-deethylation with an IC 50 value of 1.7μM and a K i value of 2.6 μM. 4,5-Dimethoxycanthin-6-one, as an alkaloid, is isolated from the wood of Picrasma quassioides BENNET (Simaroubaceae). In Vitro 4,5-Dimethoxycanthin-6-one is a potent and uncompetitive inhibitor of CYP1A2-mediated phenacetin O-deethylation with an IC 50 value of 1.7μM and a K i value of 2.6 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

生化机理

4,5-二甲氧基黄嘌呤-6-酮是 CYP1A2 介导的苯乙酸 O-脱乙基作用的一种强效非竞争性抑制剂，其 IC 50 值为 1.7 μM，K i 值为 2.6 μM。4,5-Dimethoxycanthin-6-one 作为一种生物碱，是从 Picrasma quas 的木材中分离出来的。

CAS号

18110-87-7(DMSO)

分子式

C16H12N2O3

分子量

280.28 g/mol

Smiles

O=C1N2C3=C(N=CC=C3C4=C2C=CC=C4)C(OC)=C1OC

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

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