Dapaconazole, as an antifungal agent, inhibits sterol 14α-demethylase cytochrome P450 activity with an IC 50 of 1.4 μM In Vitro Dapaconazole inhibits sterol 14α-demethylase cytochrome P450 activity with an IC 50 of 1.4 ± 0.3 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo Dapaconazole (20 mg/kg; p.o.) shows that the bioavailability is 97.3 % . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male beagle dogs Dosage: 20 mg/kg (Pharmacokinetic Analysis) Administration: P.o. Result: Showed that the bioavailability was 97.3 %. Form:Solid IC50& Target:CYP26 1.4 μM (IC 50 )