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Product details

名称

DUB-IN-1

别名

配音-IN-1

英文名称

DUB-IN-1

货号

D656217-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

DUB-IN-1 is an active inhibitor of ubiquitin-specific proteases (USPs) , with an IC 50 of 0.85 μM for USP8 In Vitro DUBs-IN-1 (22 d) is an active inhibitor of ubiquitin-specific proteases, with an IC 50 of 0.85 μM for USP8. DUBs-IN-1 is inactive toward USP7 (IC 50 , >100 μM). DUBs-IN-1 and its analogs reduce the viability of HCT116 colon and PC-3 prostate cancer cell lines with IC 50 s ranging from 0.5 μM to 1.5 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:IC50: 0.24 μM (USP8)

生化机理

DUB-IN-1 是泛素特异性蛋白酶（USP）的活性抑制剂，对 USP8 的 IC 50 为 0.85 μM。

CAS号

924296-18-4(DMSO)

分子式

C20H11N5O

分子量

337.33 g/mol

Smiles

N#CC1=C(C#N)N=C2C(/C(C3=C2C=CC=C3)=N/OCC4=CC=CC=C4)=N1

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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