10β,17β-dihydroxyestra-1,4-dien-3-one

10β,17β-二羟基雌甾-1,4-二烯-3-酮

10β,17β-dihydroxyestra-1,4-dien-3-one

D656697-1ml

1ml

10mM in DMSO

-80℃储存

超低温冰袋运输

10β,17β-dihydroxyestra-1,4-dien-3-one (DHED) is a brain-targeting bioprecursor proagent of the main human estrogen , 17β-estradiol, alleviates hot flushes in rat models of thermoregulatory dysfunction of the brain. In Vivo 10β,17β-dihydroxyestra-1,4-dien-3-one (DHED), is an inactive bioprecursor prodrug of 17β-estradiol converting to 17β-estradiol only in the brain. DHED as an E2-bioprecursor may be a viable approach for delivering E2 selectively into the brain for the potential treatment of hot flushes . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

10β,17β-二羟基雌甾-1,4-二烯-3-酮（DHED）是人类主要雌激素 17β-estradiol 的一种脑靶向生物前体，它能缓解大鼠脑体温调节功能障碍模型中的潮热症状。

549-02-0(DMSO)

C18H24O3

288.38 g/mol

CC12CCC3C(C1CCC2O)CCC4=CC(=O)C=CC34O