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名称

DC-BPi-11 hydrochloride

别名

DC-BPi-11盐酸盐

英文名称

DC-BPi-11 hydrochloride

货号

D658771-5mg

包装规格

5mg

浓度

≥97%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

DC-BPi-11 hydrochloride 是溴域 PHD 指转录因子 (BPTF) 的抑制剂，IC50 为 698 nM。DC-BPi-11 hydrochloride 对白血病细胞增殖有显著抑制作用。 DC-BPi-11 hydrochloride is an inhibitor of bromodomain PHD finger transcription factor (BPTF), with an IC 50 value of 698 nM. DC-BPi-11 hydrochloride shows remarkable inhibition against leukemia cell proliferation. Appearance:Solid IC50& Target:698 nM (BPTF) In Vitro:DC-BPi-11 hydrochloride (0.1 nM-1 μM; 24 h) inhibits BPTF in human leukemia MV-4-11 cells with an EC 50 value of 120 nM. DC-BPi-11 hydrochloride (0.01 μM-100 μM; 24 h) significantly inhibits the proliferation of human leukemia MV-4-11 cells (IC 50 =0 Biological Activity:DC-BPi-11 hydrochloride is an inhibitor of bromodomain PHD finger transcription factor (BPTF), with an IC 50 value of 698 nM. DC-BPi-11 hydrochloride shows remarkable inhibition against leukemia cell proliferation.

CAS号

2758411-61-7(free basis)

溶解性

DMSO : 10 mg/mL (23.04 mM; ultrasonic and warming and heat to 60°C)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

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