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名称

Dalazatide TFA

别名

达拉扎肽TFA

英文名称

Dalazatide TFA

货号

D659042-5mg

包装规格

5mg

浓度

≥98%

储存温度

干燥,-80℃储存

运输条件

超低温冰袋运输

产品介绍

Dalazatide (ShK-186) TFA is a specific Kv1.3 potassium channel peptide inhibitor. Dalazatide TFA can be used in the study of autoimmune diseases such as multiple sclerosis (MS), lupus erythematosus, psoriasis, rheumatoid arthritis, type 1 diabetes and inf Appearance:Solid IC50& Target:Kv1.3 In Vitro:Dalazatide (ShK-186) (0-1000 pM) TFA blocks the Kv1.3 current in the Ova-specific GFP+ effector memory T (Tem) cells in a dose-dependent manner with a K d of 65 ± 5 pM. Dalazatide (0-100 nM; 3 days) TFA inhibits CCR7 − T cell proliferation in a dose- In Vivo:Dalazatide (ShK-186) (100 μg/kg; s.c.; once) TFA inhibits delayed-type hypersensitivity and suppresses the in vivo motility and activation of Tem cells in rats. MCE has not independently confirmed the accuracy of these methods. They are for reference Biological Activity:Dalazatide (ShK-186) TFA is a specific Kv1.3 potassium channel peptide inhibitor. Dalazatide TFA can be used in the study of autoimmune diseases such as multiple sclerosis (MS), lupus erythematosus, psoriasis, rheumatoid arthritis, type 1 diabetes and inf

分子式

C186H297F3N57PS7

分子量

4556.1 g/mol

溶解性

H2O Peptide Solubility and Storage Guidelines: 1.Calculate the length of the peptide. 2.Calculate the overall charge of the entire peptide according to the following table: Contents Assign value Acidic amino acid Asp (D), Glu (E),

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

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