Share to

Details

Safety

Technical Documents

Articles

reviews

Consult

returns

Product details

名称

DB008

英文名称

DB008

货号

D659286-5mg

包装规格

5mg

级别

Moligand™

浓度

≥98%

储存温度

2-8°C储存,避光,干燥

运输条件

冰袋运输

产品介绍

DB008 is potent and selective PARP16 inhibitor with an IC 50 value of 0.27 μM, containing an acrylamide electrophilic reagent. DB008 is membrane-permeable and marks PARP16 selectively. Appearance:Solid IC50& Target:PARP16 0.27 μM (IC 50 ) In Vitro:DB008 (0-1μM; 0-120 min; HEK 293T cells) covalently modifies Cys169 of PARP16 and exhibits excellent proteome-wide selectivity in the irreversible binding mode. DB008 (100 nM; 16 h; HAP1 WT and HAP1 PARP16 KO cells) rescues nutrient starvation-induce Biological Activity:DB008 is potent and selective PARP16 inhibitor with an IC 50 value of 0.27 μM, containing an acrylamide electrophilic reagent. DB008 is membrane-permeable and marks PARP16 selectively.

分子式

C25H21FN4O3

分子量

444.46 g/mol

Smiles

O=C1NN=C(CC2=CC=C(F)C(C(N3CCN(C(C=C)=O)CC3)=O)=C2)C4=C1C=CC(C#C)=C4

溶解性

DMSO : 100 mg/mL (224.99 mM; Need ultrasonic)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！