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Product details

名称

二肽基肽酶VIII 人

货号

D755260-10μg

包装规格

10μg

级别

重组

浓度

expressed in Sf9 cells

产品介绍

人二肽基肽酶VIII已用于将ERGIC-53鉴定为α1-抗胰蛋白酶的细胞内转运受体的研究中。人二肽基肽酶VIII也已用于研究ERGIC-53/MCFD2转运受体复合物的货物选择性。 Human dipeptidyl peptidase VIII has been used in a study to identify ERGIC-53 as an intracellular transport receptor of α1-antitrypsin. Human dipeptidyl peptidase VIII has also been used in a study to investigate the cargo selectivity of the ERGIC-53/MCFD2 transport receptor complex.

生化机理

二肽基肽酶VIII（DPP8）是在细胞质中表达的100 kDa单体蛋白。它是一种后脯氨酸二肽基氨肽酶，与DPPIV和成纤维细胞活化蛋白（FAP）同源。它水解Ala-Pro、Arg-Pro和Gly-Pro。DPP8具有最佳的中性pH值。它可能参与T细胞活化和免疫功能，因为它与DPPIV相似。它在免疫激活过程中被上调。

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

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