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名称

Dipeptidyl Peptidase IX human

英文名称

Dipeptidyl Peptidase IX human

货号

D755261-10μg

包装规格

10μg

级别

重组

浓度

expressed in Sf9 cells

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

DPP9 is a protease of the DPP4 gene family that is used in cancer research to study the regulation of survival and proliferation pathways. DPP9 is used to study cell-extracellular matrix interactions and tissue remodeling. DPP9 is a protease of the DPP4 gene family that is used in cancer research to study the regulation of survival and proliferation pathways . DPP9 is used to study cell-extracellular matrix interactions and tissue remodeling .

生化机理

DPP IX 是二肽基肽酶 S9b 家族的成员，能裂解肽类激素胰高血糖素样肽-1、胰高血糖素样肽-2、神经肽 Y 和肽 YY，与二肽基肽酶 IV 相比，其动力学差异明显。它通过调节分子信号级联在调节细胞存活和增殖方面发挥作用。在人肝癌细胞（HepG2 和 Huh7）和人胚胎肾细胞（HEK293T）中过量表达人 DPP9 可显著抑制蛋白激酶 B 的活化。 DPP9 被认为会影响细胞与细胞外基质的相互作用，并可能参与组织重塑的调控。

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

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