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Product introduction

Proligo′s DNA phosphoramidites lead to high-yield and high-quality oligonucleotides due to their high coupling efficiency. The deprotection step of automated oligonucleotide synthesis is integral to synthesis time and final product quality. Exocyclic amine functions are protected by a benzoyl group (dA(bz) and dC(bz)) or isobutyryl group (dG(ib))Key features of DNA phosphoramidites: · Recommended cleavage and deprotection conditions are 8 hours at 55 °Cor 24 hours at room temperature using concentrated ammonia solution, for standard base-protected oligonucleotides · The high coupling efficiency of Proligo′s DNA phosphoramidites leads to high-yield and high-quality oligonucleotides The product belongs to MerMade synthesizers.

Specs ⸢ View details ⸥

Chinese name

DMT-dA(Bz)亚磷酰胺

English name

DMT-dA(bz) Phosphoramidite

Chinese alias

N-苯甲酰基-5'-O-(4,4'-二甲氧基三苯甲基)-2'-脱氧腺苷-3'-(2-氰乙基-N,N-二异丙基)亚磷酰胺 | N-苯甲酰基-5'-O-[双(4-甲氧基苯基)(苯基)甲基]-3'-O-[(2-氰基乙氧基)(二异丙基氨基)膦基]-2'-脱氧腺苷

English alias

DMT-dA(bz) Phosphoramidite, configured for MerMade | 5'-O-DMT-N6-Benzoyl-2'-Deoxyadenosine-CE Phosphoramidite | (2R,3S,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphor

CAS number

98796-53-3

molecular formula

C47H52N7O7P

molecular weight

857.93 g/mol

Exact mass

≥99%

PSA

155.000 Å²

Logp

6.800

Technical Documents

98796-53-3 | DMT-dA(bz) Phosphoramidite.pdf
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