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Product introduction

(E/Z)-Droloxifene is a mixture of (E)-droloxifene (a selective estrogen receptor modulator ) and (Z)-droloxifene. (E)-Droloxifene binds to the estrogen receptor ( ER ) with an IC 50 value of 24 nM in rabbit uterine homogenates. (E)-Droloxifeneincreases uterine weight in immature rats, and reduces estradiol-induced increases in uterine weight in juvenile rats. (E)-Droloxifene also inhibits 17β-estradiol-stimulated growth of MCF-7, ZR-75-1, and T47D human breast cancer cells. (Z)-Droloxifene binds weakly to ER and has no estrogenic or antiestrogenic activity.

Specs ⸢ View details ⸥

Chinese name

(E/Z)-Droloxifene

English name

(E/Z)-Droloxifene

Chinese alias

English alias

CAS number

165813-01-4

molecular formula

C26H29NO2

molecular weight

387.51 g/mol

Exact mass

PSA

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