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Product introduction

ERK抑制剂II，阴性对照是可透过细胞的吡唑并吡嗪醇，可作为ERK抑制剂II的（-）对照。ERK抑制剂II，阴性对照已显示出对ERK1和ERK2几乎没有活性，或在Mv1Lu上皮细胞中阻断TGF-β诱导的AP-1活化。 ERK Inhibitor II, Negative Control is a cell-permeable pyrazolopyridazinol that serves as a (-) control for ERK Inhibitor II. ERK Inhibitor II, Negative Control has been shown to exhibit little activity towards ERK1 and ERK2 or in blocking TGF-β-induced AP-1 activation in Mv1Lu epithelial cells.

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Chinese name

ERK抑制剂II，阴性对照

English name

ERK Inhibitor II, Negative Control

Chinese alias

English alias

5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ol | HY-112469 | 5-{2-phenylpyrazolo[1,5-a]pyridin-3-yl}-1H,2H,3H-pyrazolo[3,4-c]pyridazin-3-one | Q27077222 | 1177970-73-8 | DTXSID10587897 | SCHEMBL16114097 | ERK Inhibitor II (Negat

CAS number

1177970-73-8

molecular formula

C18H12N6O

molecular weight

328.3 g/mol

Exact mass

PSA

84.200 Å²

Logp

1.9

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