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Product introduction

恩替诺司他是苯甲酰胺类化合物，由p-(氨基甲基)苯甲酸的吡啶-3-基甲基氨基甲酸酯衍生物的羧基与苯-1,2-二胺的一个氨基缩合而成。它是组蛋白去乙酰化酶同工型1(HDAC1)和同工型3(HDAC3)的抑制剂。它具有抗肿瘤剂、EC 3.5.1.98(组蛋白去乙酰化酶)抑制剂和凋亡诱导剂的作用。它是苯甲酰胺类、氨基甲酸酯、吡啶类、取代苯胺和一级氨基化合物。它与1,2-苯二胺功能相关。

Specs ⸢ View details ⸥

Chinese name

恩替诺特 (MS-275), 组蛋白去乙酰化酶抑制剂

English name

pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate

Chinese alias

恩替诺特

English alias

SNDX-275 | SB16665 | D09338 | MLS006010183 | AC-8968 | MS-275, A HDAC1 and HDAC3 inhibitor | NSC756642 | NSC-756642 | DB11841 | Carbamic acid, 3-pyridinylmethyl ester | MS-275,Entinostat, SNDX-275, MS-27-275 | W-201831 | N-[[4-[[(2-Aminophenyl)amino]carbo

CAS number

209783-80-2

molecular formula

C21H20N4O3

molecular weight

376.4

Exact mass

PSA

106

Logp

Safety

Hazard categories and classifications： Repr. 1B (37.8%)

Technical Documents

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Consultation

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