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Product introduction

Information EIDD-1931 EIDD-1931 (Beta-d-N4-hydroxycytidine, β-d-N4-hydroxycytidine, NHC) is an active metabolite of EIDD-2801, a promising COVID-19 inhibitor. EIDD-1931 (NHC) has broad spectrum antiviral activity against SARS-CoV-2 , MERS-CoV , SARS-CoV , and related zoonotic group 2b or 2c Bat-CoVs with average IC50 of 0.15 μM, as well as increased potency against a coronavirus bearing resistance mutations to the nucleoside analog inhibitor remdesivir.

Specs ⸢ View details ⸥

Chinese name

N4-羟基胞苷

English name

N4-Hydroxycytidine

Chinese alias

English alias

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one | N-hydroxycytidine | 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(hydroxyimino)-3,4-dihydropyrimidin-2(1H)-one | 4-oxime uridine | SU

CAS number

3258-02-4

molecular formula

C9H13N3O6

molecular weight

259.22 g/mol

Exact mass

PSA

135.000 Å²

Logp

-2.200

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