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Product introduction

Eflornithine(Difluoromethylornithine)通过对鸟氨酸脱羧酶的不可逆抑制作用，抑制多胺生物合成。它是一种化疗保护剂，可阻止血管生成。其生物半衰期为8小时。 Eflornithine(Difluoromethylornithine) inhibits polyamine biosynthesis by the selective, irreversible inhibition of ornithine decarboxylase (ODC). A chemoprotective agent that blocks angiogenesis. Its biological half-life is 8 hours. A cell-permeable, anticancer agent that acts as a specific and irreversible inhibitor of ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine biosynthesis. Inhibits B16 melanoma-induced angiogenesis in ovo and proliferation of vascular endothelial cells in vitro.

Specs ⸢ View details ⸥

Chinese name

依氟鸟氨酸盐酸盐一水合物, 鸟氨酸脱羧酶抑制剂

English name

Eflornithine hydrochloride hydrate

Chinese alias

依氟鸟氨酸盐酸盐一水合物 | DL-α-二氟甲基鸟氨酸盐酸盐一水合物

English alias

CAS number

96020-91-6

molecular formula

C6H12F2N2O2·HCl·H2O

molecular weight

236.65 g/mol

Exact mass

≥98%(T)

PSA

90.300 Å²

Logp

Technical Documents

96020-91-6 | EFLORNITHINE HYDROCHLORIDE.pdf
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