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Product introduction

Evifacotrep, a short transient receptor potential channel 5 and 4 ( TRPC5 / TRPC4 ) antagonist (WO2020061162, compound 100), can be used for the research of neurological diseases. Evifacotrep targets to TRPC5 / TRPC4 with IC 50 s ≤50 nM In Vitro Evifacotrep (1 μM; 24 h) inhibits cell growth in ICLN-1694 cells(HEK-TRExhTRPC4). MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo Evifacotrep (30 mg/kg; sc; once daily or twice daily for 10 days) results in reduced urinary albumin excretion on following injury with puromycinaminonucleoside (PAN) . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:TRPC5

Specs ⸢ View details ⸥

Chinese name

Evifacotrep

English name

Evifacotrep

Chinese alias

艾维法科特雷普

English alias

CAS number

2413739-88-3

molecular formula

C18H12ClF4N5O2

molecular weight

441.77 g/mol

Exact mass

≥99%

PSA

79.700 Å²

Logp

3.100

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