肠激酶 来源于猪肠

E755304-1.5KU

1.5KU

≥0.5 units/mg solid

来自Sigma的酶已用于激活胰蛋白酶原，以测量猪胰腺中胰蛋白酶的活性。研究表明，抗菌治疗可减少断奶猪肠道菌群，提高蛋白消化能力，而不会改变绒毛结构。来自猪肠的肠激酶已用于一项研究中，以报告异常胰胆连接的新实验模型。来自猪肠的肠激酶也已用于研究胃抑制性多肽的促胰岛素区域的研究中。 Enterokinase from porcine intestine has been used in a study to report a new experimental model of the anomalous pancreatico-biliary junction. Enterokinase from porcine intestine has also been used in a study to investigate the insulinotropic region of the gastric inhibitory polypeptide. The enzyme from Sigma has been used for the activation of trypsinogen in order to measure the activity of trypsin in hog pancreas. The study showed that antimicrobial treatment reduces intestinal microflora and improves protein digestive capacity without changes in villous structure of weanling pigs.

肠激酶是一种膜结合的丝氨酸蛋白酶，可特异性和快速地将胰蛋白酶原转化为胰蛋白酶，从而触发其他酶原向活性酶的转化。它的分子量约为150 kDa。该酶是由35-47 kDa亚基组成的异二聚体。轻链和重链通过两个二硫键连接。它是一种含有35%碳水化合物的糖蛋白。胰蛋白酶原的多肽链仅在-（Asp） 4 -Lys-序列后水解。该酶被大豆胰蛋白酶抑制剂抑制。肠激酶通常用于蛋白修饰和氨基酸序列测定。