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Product introduction

Lenvatinib (E7080)是一种多靶点抑制剂，作用于VEGFR2(KDR)/VEGFR3(Flt-4)最有效，IC50为4 nM/5.2，对VEGFR1/Flt-1作用效果稍弱，作用于VEGFR2/3比作用于FGFR1， PDGFRα/β选择性高10倍左右。Phase 3。 Lenvatinib is an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors. Lenvatinib (E7080) is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β. Phase 3. Lenvatinib is an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors.

Specs ⸢ View details ⸥

Chinese name

乐伐替尼 (E7080), FMS 相关受体酪氨酸激酶 4 抑制剂

English name

Lenvatinib (E7080)

Chinese alias

English alias

LENVATINIB [MI] | UNII-EE083865G2 | AS-16203 | LEV | NSC800781 | NSC-800781 | DB09078 | AKOS021983298 | LENVATINIB [INN] | AKOS015838040 | BCP9000633 | DTXSID30182868 | 4-(3-Chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide

CAS number

417716-92-8

molecular formula

C21H19ClN4O4

molecular weight

426.85 g/mol

Exact mass

PSA

116.000 Å²

Logp

2.8

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Research chemical CAS 417716-92-8 10mM 1ml

Name: Research chemical CAS 417716-92-8 10mM 1ml
Brand: 麦克林
SKU: E794871-1ml

Research chemical CAS 417716-92-8 10mM 1ml, complete specifications, for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：E794871-1ml

Product model：1ml

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Lead Time：30days

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Research chemical CAS 417716-92-8 10mM 1ml

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