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Product details
名称
纤维蛋白原,来源于牛血浆
货号
F335288-1g
包装规格
1g
浓度
50-70% protein (≥85% of protein is clottable)
产品介绍
纤维蛋白原(Fibrinogen,Fg),即凝血因子I,分子量约为340KDa,纤维蛋白原为共价二聚体,由2条α链、2条β链、2条γ链三对不同的多肽链组成,各肽键间彼此通过二硫键相连。α链分子量63.5KDa分子量56KDa,γ链分子量47KDa,两个亚基在肽链N-末端附近通过三对二硫键将对称的两个亚基连接起来形成中间球状物。 纤维蛋白原参与凝血的原理:在凝血酶作用下,α链与β链分别释放出A肽与B肽,生产纤维蛋白单体。在此过程中,由于释放了酸性多肽,负电性降低,单体易于聚合成纤维蛋白多聚体,但此时单体之间借氢键与疏水键相连,尚可溶于稀酸和尿素溶液中。近一步在Ca²+与活化的XIII因子(谷氨酰胺转移酶,纤维蛋白稳定因子)作用下,单体之间以共价键相连,则变成稳定的不溶性纤维蛋白凝块,完成凝血过程。此外,纤维蛋白原还参与体内炎症、组织损伤、组织修复等一系列病理和生理过程。
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Research chemical 1g; 70%; ≥85%

Research chemical 1g; 70%; ≥85%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1g; 70%; ≥85%.

item number:F335288-1g
Product model:1g
level: 1g; 70%; ≥85%
Lead Time:30days
sold 138 Items
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