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Product introduction

Description Quasi-orthogonally-protected Glu derivative.The Dmab group can be removed selectively in the presence of tBu-based protecting groups by treatment with 2% hydrazine in DMF [1], making this derivative an extremely useful tool for the preparation of cyclic peptides by Fmoc SPPS or for library synthesis. For the on-resin synthesis of side-chain to side-chain lactam bridged peptides, the combination of Lys(ivDde) and Glu(ODmab) is particularly advantageous since both side-chains can be simultaneously unmasked in a single step.The product number for this product was previously 04-12-1174..

Specs ⸢ View details ⸥

Chinese name

Fmoc-Glu-ODmab

English name

Fmoc-Glu-ODmab

Chinese alias

English alias

N-α-Fmoc-L-glutamic acid α-4-{N-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]-amino} benzyl ester, Fmoc-Glu-ODmab

CAS number

172611-75-5

molecular formula

C40H44N2O8

molecular weight

680.79 g/mol

Exact mass

Reagent Grade

PSA

152.000 Å²

Logp

6.500

Technical Documents

172611-75-5 | Fmoc-Glu-ODmab Novabiochem®.pdf
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