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Product introduction

FK614 是一种非噻唑烷二酮 (TZD) 型选择性 PPARγ 调节剂 (SPPARM)。FK614 是一种 PPARγ 激动剂，显示出强大的抗糖尿病活性。FK614 在脂肪细胞分化的各个阶段对 PPARγ 的激活有不同的影响。FK614 可用于研究高血糖、高甘油三酯血症、糖耐量异常和 2 型糖尿病。 FK614 is non-thiazolidinedione (TZD) type, and selective PPARγ modulator (SPPARM). FK614 functions as a PPARγ agonist with potent anti-diabetic activity in vivo. FK614 has different effects on the activation of PPARγ at each stage of adipocyte differentiation. FK614 can be used for the research of hyperglycemia, hypertriglyceridemia, glucose intolerance and type 2 diabetes .

Specs ⸢ View details ⸥

Chinese name

FK614, 过氧化物酶体增殖激活受体伽马调节剂

English name

FK614

Chinese alias

English alias

UNII-V5Q32BZX79 | FK614 | FK-614 | ATx08-001 | 1-(2,4-dichlorobenzyl)-2-methyl-N-(pentylsulfonyl)-1H-benzo[d]imidazole-6-carboxamide | FK 614 | 1H-Benzimidazole-6-carboxamide,1-[(2,4-dichlorophenyl)methyl]-2-methyl-N-(pentylsulfonyl)- | V5Q32BZX79 | ATx-0

CAS number

193012-35-0

molecular formula

C21H23Cl2N3O3S

molecular weight

468.40 g/mol

Exact mass

≥99%

PSA

89.400 Å²

Logp

5.3

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