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名称

Fz7-21 TFA

别名

Fz7-21三氟乙酸

英文名称

Fz7-21 TFA

货号

F659200-5mg

包装规格

5mg

浓度

≥99%

储存温度

干燥,-80℃储存

运输条件

超低温冰袋运输

产品介绍

Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) TFA is a potent peptide antagonist of FZD7 receptors , selectively binds to FZD7 CRD subclass and alters the conformation of the CRD and the architecture of its lipid-binding groove. The EC 50 values are 58 and 34 nM for hum Appearance:Solid IC50& Target:EC50: 58 nM (human FZD7 CRD), 34 nM (mouse FZD7 CRD) In Vitro:Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) TFA (0-100 μM; 6 h; HEK293-TB cells) impairs Wnt signaling with IC 50 value of 100 nM. Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) TFA (1 µM) blocks WNT3A-mediated stabilization of β-catenin in mouse L cells with IC 50 value of 50 n Biological Activity:Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) TFA is a potent peptide antagonist of FZD7 receptors , selectively binds to FZD7 CRD subclass and alters the conformation of the CRD and the architecture of its lipid-binding groove. The EC 50 values are 58 and 34 nM for hum

分子式

C85H115N18F3O25S2

分子量

1910.07 g/mol

溶解性

DMSO : 33.33 mg/mL (17.45 mM; Need ultrasonic) H2O : ＜ 0.1 mg/mL (insoluble)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

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「No technical documents」

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