FABPs ligand 6

FABPs 配体 6

FABPs ligand 6

F659237-5mg

5mg

≥98%

2-8°C储存,避光

冰袋运输

FABPs ligand 6 (MF6) is an FABP5 and FABP7 inhibitor with K D values of 874 nM and 20 nM, respectively. FABPs ligand 6 can be used for multiple sclerosis research. Appearance:Solid IC50& Target:K D : 20 nM (FABP7), 874 nM (FABP5) In Vitro:FABPs ligand 6 (MF6) rescues mitochondrial function by blocking voltagedependent anion channel (VDAC)-1-dependent mitochondrial macropore formation induced by psychosine in KG-1C cells, a FABP5- mediated injury. MCE has not independently confirmed th In Vivo:MF 6 (1mg/kg; i.g.; daily for 4 weeks) improves the severity of EAE (experimental autoimmune encephalomyelitis) and attenuates oxidative levels and the inflammatory response. MCE has not independently confirmed the accuracy of these methods. They ar Biological Activity:FABPs ligand 6 (MF6) is an FABP5 and FABP7 inhibitor with K D values of 874 nM and 20 nM, respectively. FABPs ligand 6 can be used for multiple sclerosis research.

C28H27FN2O3

458.52 g/mol

CC(C)C1=CC=C(N2C(C3=CC=CC=C3)=CC(C4=C(OCCCC(O)=O)C=CC(F)=C4)=N2)C=C1

DMSO : 125 mg/mL (272.62 mM; Need ultrasonic)